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更新時(shí)間：2025-06-29
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DKK-1檢測(cè)試劑盒
直接測(cè)定，無(wú)需樣本稀釋
貨號(hào)：BI-20413
DKK-1 是Wnt 信號(hào)通路的抑制劑
BI-20413與BI-20412對(duì)比
檢測(cè)特點(diǎn) | BI-20413 | BI-20412 |
孵育時(shí)間 | 2h/1h/30min | overnight |
樣品處理 | 直接測(cè)定 | 需要1:4稀釋 |
標(biāo)準(zhǔn)品范圍 | 0-160pmol/L | 0-50pmol/L |
應(yīng)用領(lǐng)域：
試劑盒特點(diǎn)：
檢測(cè)方法：夾心ELISA，HRP/TMB顯色
樣本類型：血清
樣品量：20ul/test
標(biāo)準(zhǔn)品范圍：0-160 pmol/L
檢測(cè)靈敏度：1.7pmol/L
孵育條件：2h/1h/30min
產(chǎn)品優(yōu)勢(shì)：
參考文獻(xiàn)
1 | Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin and Dickkopf-1 Levels of Naive Postmenopausal Women With Low Bone Mass: A Randomized, Head-to-Head Clinical Trial. Athanasios D. Anastasilakis, et al. J. Clin. Endocrinol. Metab., Aug 2013; 98: 3206 - 3212. |
2 | Elevated Serum Dickopff-1 Levels Increase Risk of Hip and Vertebral Fracture in Older Caucasian Women. Aarthi Arasu,et al. Endocr. Rev., Jun 2013; 34: SAT-224. |
3 | Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis. Diederik P C de Rooy,et al. Ann Rheum Dis, May 2013; 72: 769 - 775. |
4 | High dickkopf-1 levels in sera and leukocytes from children with 21- hydroxylase deficiency on chronic glucocorticoid treatment. Giacomina Brunetti,et al. Am J Physiol Endocrinol Metab, Mar 2013; 304: E546 - E554. |
5 | Sclerostin and DKK1 in postmenopausal osteoporosis treated with denosumab. D Gatti,et al. J Bone Miner Res, Nov 2012; 27(11): 2259-63. |
6 | Sclerostin Levels Associated with Inhibition of the Wnt/β-Catenin Signaling and Reduced Bone Turnover in Type 2 Diabetes Mellitus. Agostino Gaudio,et al. J. Clin. Endocrinol. Metab., Oct 2012; 97: 3744 - 3750. |
7 | Serum Osteoprotegerin, RANKL, and Dkk-1 Levels in Adults with Langerhans Cell Histiocytosis. Polyzois Makras,et al. J. Clin. Endocrinol. Metab., Apr 2012; 97: E618 - E621 |
8 | High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis. Gisela Ruiz Heiland,et al. Ann Rheum Dis, Apr 2012; 71: 572 - 574. |
9 | Assessment of circulating Dickkopf-1 with a new two-site immunoassay in healthy subjects and women with breast cancer and bone metastases. N Voorzanger-Rousselot, et al. Calcif Tissue Int, May 1, 2009; 84(5): 348-354 |
10 | Circulating Dickkopf-1 and Radiological Progression in Patients with Early Rheumatoid Arthritis Treated with Etanercept. Patrick Garnero,et al. J Rheumatol, Oct 2008. |
11 | Increased Sclerostin Serum Levels Associated with Bone Formation and Resorption Markers in Patients with Immobilization-Induced Bone Loss. Agostino Gaudio,et al. J. Clin. Endocrinol. Metab., May 2010; 95: 2248 - 2253. |
12 | High Serum Sclerostin Correlates with Advanced Stage, Increased Bone Resorption, Reduced Osteoblast Function, and Poor Survival in Newly-Diagnosed Patients with Multiple Myeloma. Evangelos Terpos,et al. Blood (ASH Annual Meeting Abstracts), Nov 2009; 114: 425. |
13 | The Effect of Zoledronic Acid on Serum Dickkopf-1, Osteoprotegerin, and RANKL in Patients with Paget's Disease of Bone. S A Polyzos, et al. Horm Metab Res, Aug 2009 |
14 | Glucocorticoids Attenuate the Stimulatory Effect on Bone Formation by Bortezomib. Thomas Lund,et al. Blood (ASH Annual Meeting Abstracts), Nov 2008; 112: 5183. |
